Transition-metal-free decarboxylation of dimethyl malonate: an efficient construction of α-amino acid esters using TBAI/TBHP.
نویسندگان
چکیده
A transition-metal-free decarboxylation coupling process for the preparation of α-amino acid esters, which succeeded in merging hydrolysis/decarboxylation/nucleophilic substitution, is well described. This strategy uses commercially available inexpensive starting materials, catalysts and oxidants and has a wide substrate scope and operational simplicity.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 13 13 شماره
صفحات -
تاریخ انتشار 2015